Clinical Studies on Chronic Nitrous Exposure [Why Scavenging is So Important]

Controlling Exposures to Nitrous Oxide During Anesthetic Administration

Controlling Exposures to Nitrous Oxide During Anesthetic Administration1

The National Institute for Occupational Safety and Health (NIOSH) requests assistance in controlling exposures of workers to nitrous oxide (N2O) during the administration of anesthetic gas in medical, dental, and veterinary operatories.

Reduced Fertility Among Women Employed as Dental Assistants Exposed to High Levels of Nitrous Oxide

Reduced Fertility Among Women Employed as Dental Assistants Exposed to High Levels of Nitrous Oxide2

Epidemiologic studies have suggested an association between exposure to mixed anesthetic gases and impaired fertility. We investigated the effects of occupational exposure to nitrous oxide on the fertility of female dental assistants.

Toxicity of bone marrow in dentists exposed to nitrous oxide

Toxicity of Bone Marrow in Dentists Exposed to Nitrous Oxide3

This study provides direct evidence that occupational exposure to nitrous oxide may cause depression of vitamin B12 activity resulting in measurable changes in bone marrow secondary to impaired synthesis of deoxyribonucleic acid.

Serum Methionine and Hepatic Enzyme Activity in Anaesthetists Exposed to Nitrous Oxide

Serum Methionine and Hepatic Enzyme Activity in Anaesthetists Exposed to Nitrous Oxide4

Normal serum concentrations of methionine, leucine, isoleucine and valine have been found in 10 anaesthetists using nitrous oxide under their regular working conditions without scavenging of patients’ exhaled gas.

American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults

American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults5

The American Geriatrics Society (AGS) Beers Criteria® (AGS Beers Criteria®) for Potentially Inappropriate Medication (PIM) Use in Older Adults are widely used by clinicians, educators, researchers, healthcare administrators, and regulators.

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Clinical Studies on Chronic Nitrous Exposure

[Why Scavenging is So Important]

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Clinical Studies on Safety of Nitrous Oxide

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  1. CDC – NIOSH Publications and Products – Controlling Exposures to Nitrous Oxide During Anesthetic Administration (94-100), May 2020
  2. The New England Journal of Medicine, October 1, 1992
  3. British Medical Journal, Volume 291, August 31, 1985
  4. British Journal of Anaesthesia, 1982, 54, 593
  5. 2019 AGS Beers Criteria® Update Expert Panel Month 2019–VOL. 00, NO. 00 JAGS
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