The National Institute for Occupational Safety and Health (NIOSH) requests assistance in controlling exposures of workers to nitrous oxide (N2O) during the administration of anesthetic gas in medical, dental, and veterinary operatories.
Reduced Fertility Among Women Employed as Dental Assistants Exposed to High Levels of Nitrous Oxide2
Epidemiologic studies have suggested an association between exposure to mixed anesthetic gases and impaired fertility. We investigated the effects of occupational exposure to nitrous oxide on the fertility of female dental assistants.
This study provides direct evidence that occupational exposure to nitrous oxide may cause depression of vitamin B12 activity resulting in measurable changes in bone marrow secondary to impaired synthesis of deoxyribonucleic acid.
Normal serum concentrations of methionine, leucine, isoleucine and valine have been found in 10 anaesthetists using nitrous oxide under their regular working conditions without scavenging of patients’ exhaled gas.
American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults5
The American Geriatrics Society (AGS) Beers Criteria® (AGS Beers Criteria®) for Potentially Inappropriate Medication (PIM) Use in Older Adults are widely used by clinicians, educators, researchers, healthcare administrators, and regulators.
Clinical Studies on Chronic Nitrous Exposure
[Why Scavenging is So Important]
Clinical Studies on Safety of Nitrous Oxide
Nitrouseal® Instructions for Use [IFU]
Frequently Requested Forms
Office Based Surgery Laws
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- CDC – NIOSH Publications and Products – Controlling Exposures to Nitrous Oxide During Anesthetic Administration (94-100), May 2020
- The New England Journal of Medicine, October 1, 1992
- British Medical Journal, Volume 291, August 31, 1985
- British Journal of Anaesthesia, 1982, 54, 593
- 2019 AGS Beers Criteria® Update Expert Panel Month 2019–VOL. 00, NO. 00 JAGS